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G protein-coupled receptors database
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G protein-coupled receptors database : ウィキペディア英語版
G protein-coupled receptors database
(GPCRdb ) contains data, web tools and diagrams for G protein-coupled receptors (GPCRs). It stores a manual annotation of all GPCR crystal structures, the largest collections of receptor mutants and reference sequence alignments. The tools run directly in the web browser allowing for swift analysis of structures, sequence similarities, receptor relationships, and ligand target profiles. Diagrams illustrate receptor sequences (snake-plot and helix box diagrams) and relationships (phylogenetic trees).
== Background and development ==
The GPCR database, GPCRdb was started in 1993 by Gert Vriend, Ad IJzerman, Bob Bywater
and Friedrich Rippmann. Over two decades, GPCRdb evolved to be a comprehensive
information system storing and analysing data. In 2013, the stewardship of
GPCRdb was transferred to the David (Gloriam group ) at the University of
Copenhagen, backed up by an international team of contributors and developers
from the EU COST Action ‘(GLISTEN )’.
Today, GPCRdb offers reference data and easy-to-use web tools and diagrams for
a multidisciplinary audience investigating GPCR function, drug design or
evolution.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「G protein-coupled receptors database」の詳細全文を読む



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